[Cellular compatibility of type collagen I scaffold and human adipose-derived stem cells]

Nan Fang Yi Ke Da Xue Xue Bao. 2007 Feb;27(2):223-5.
[Article in Chinese]

Abstract

Objective: To study the cellular compatibility of type I collagen scaffold and human adipose-derived stem cells (ADSC(S)) in order to explore appropriate scaffold materials for adipose tissue engineering.

Methods: The morphology and function of the ADSC(S) were observed by inverted phase contrast microscope, scanning electron microscope and XTT assay when cocultured type I collagen scaffold with ADSC(S) in vitro. Cells adhesive rates were also calculated.

Result: ADSC(S) were able to attach, grow and proliferate well on the scaffolds.

Conclusion: collagen I scaffold exhibits excellent cellular compatibility and can be used as a vehicle for adipose tissue engineering.

Publication types

  • English Abstract

MeSH terms

  • Adipocytes / cytology*
  • Adult Stem Cells / cytology*
  • Biocompatible Materials / chemistry
  • Cells, Cultured
  • Coculture Techniques
  • Collagen Type I / chemistry*
  • Humans
  • Tissue Engineering / methods*
  • Tissue Scaffolds

Substances

  • Biocompatible Materials
  • Collagen Type I