Abstract
Clinical manifestation are described in children with epidemic HUS. The intestinal involvement in the prodromic period, is outlined and the most common disturbances such acute renal failure, thrombocytopenia, hemolytic anemia, leucocitosis hypertension, neurological, pancreatic and cardiac manifestations are described. We discuss the acid-base and electrolyte disturbances, metabolic acidosis, hyponatremia, hyperkalemia. The etiopathogenic treatment and the control of renal sequelae are also discussed.
MeSH terms
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Acute Disease
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Acute Kidney Injury / etiology
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Child
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Child, Preschool
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Diarrhea / complications
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Diarrhea / physiopathology
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Escherichia coli O157 / immunology
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Escherichia coli Vaccines / therapeutic use
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Female
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Hemolytic-Uremic Syndrome / complications*
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Hemolytic-Uremic Syndrome / physiopathology
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Hemolytic-Uremic Syndrome / therapy*
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Humans
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Hypertension / etiology
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Infant
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Kidney Transplantation
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Male
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Prognosis
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Thrombocytopenia / etiology
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Thrombocytopenia / physiopathology
Substances
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Escherichia coli Vaccines