Abstract
The in vitro activities of isepamicin against 117 Mycobacteria abscessus, 48 Mycobacterium fortuitum, and 20 Mycobacterium chelonae isolates were evaluated by a microdilution test. Isepamicin MIC(90)s were < or =16 microg/ml for the three species. Isepamicin was as active as amikacin and kanamycin and more active than tobramycin, capreomycin, gentamicin, and streptomycin.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Aminoglycosides / pharmacology*
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Anti-Bacterial Agents / pharmacology*
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Capreomycin / pharmacology*
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Gentamicins / pharmacology
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Humans
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Microbial Sensitivity Tests
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Mycobacterium chelonae / drug effects
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Mycobacterium fortuitum / drug effects
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Nontuberculous Mycobacteria / drug effects*
Substances
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Aminoglycosides
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Anti-Bacterial Agents
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Gentamicins
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Capreomycin
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isepamicin