Multiple cardiac metastases from a malignant melanoma

Eur J Echocardiogr. 2008 May;9(3):391-2. doi: 10.1016/j.euje.2006.12.008. Epub 2007 Mar 12.

Abstract

Metastatic tumors in the pericardium or the heart are more common than primary tumors and their incidence has increased during the last decades due to the prolonged survival of patients with cancer and the increased prevalence of the disease in the general population. We present the case of a 36-year-old patient admitted to our hospital due to fatigue, dyspnea, and episodes of dizziness and fainting during the last month. He had a history of a malignant skin melanoma surgically removed 4 years ago. The echo study identified multiple metastases in the heart involving the pericardium, the myocardium and the right atrium, where the tumor was mobile creating mechanical tricuspid valve stenosis. Malignant metastasis was confirmed by pericardiocentesis and, although treatment with chemotherapy was promptly initiated, the patient died 4 months later. Despite the difficulty in clinical diagnosis of cardiac melanoma, early detection has important therapeutic and prognostic implications. Echocardiography is the most common diagnostic modality and transesophageal approach may be the technique of choice to image intracardiac metastatic tumors.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Fatal Outcome
  • Heart Neoplasms / diagnostic imaging*
  • Heart Neoplasms / secondary
  • Humans
  • Male
  • Melanoma / diagnostic imaging*
  • Melanoma / secondary
  • Skin Neoplasms / pathology*
  • Ultrasonography