Furanocembranoids from the stem bark of Croton oblongifolius

Khanitha Pudhom; Tirayut Vilaivan; Nattaya Ngamrojanavanich; Suchon Dechangvipart; Damrong Sommit; Amorn Petsom; Sophon Roengsumran

doi:10.1021/np060520t

Furanocembranoids from the stem bark of Croton oblongifolius

J Nat Prod. 2007 Apr;70(4):659-61. doi: 10.1021/np060520t. Epub 2007 Mar 7.

Authors

Khanitha Pudhom¹, Tirayut Vilaivan, Nattaya Ngamrojanavanich, Suchon Dechangvipart, Damrong Sommit, Amorn Petsom, Sophon Roengsumran

Affiliation

¹ Research Centre for Bioorganic Chemistry, Department of Chemistry, Faculty of Science, Chulalongkorn University, Bangkok 10330, Thailand. Khanitha.P@chula.ac.th

PMID: 17341114
DOI: 10.1021/np060520t

Abstract

Four novel furanocembranoids (1-4) were isolated from the stem bark of Croton oblongifolius. Their structures were elucidated on the basis of spectroscopic analysis, mainly NMR and MS. Compounds 1, 3, and 4 exhibited good cytotoxicity against several human tumor cell lines.

MeSH terms

Antineoplastic Agents, Phytogenic / chemistry
Antineoplastic Agents, Phytogenic / isolation & purification*
Antineoplastic Agents, Phytogenic / pharmacology
Croton / chemistry*
Diterpenes / chemistry
Diterpenes / isolation & purification*
Diterpenes / pharmacology
Drug Screening Assays, Antitumor
Humans
Molecular Structure
Nuclear Magnetic Resonance, Biomolecular
Plant Bark / chemistry
Plants, Medicinal / chemistry*
Thailand

Substances

Antineoplastic Agents, Phytogenic
Diterpenes