DNA alkylation and DNA methylation: cooperating mechanisms driving the formation of colorectal adenomas and adenocarcinomas?

Gut. 2007 Mar;56(3):318-20. doi: 10.1136/gut.2006.106849.

Abstract

Defining our understanding of the association between DNA alkylation and colon carcinogenesis

Publication types

  • Comment
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Review

MeSH terms

  • Adenocarcinoma / genetics*
  • Adenoma / genetics*
  • Alkylation
  • Cell Transformation, Neoplastic / genetics*
  • Colorectal Neoplasms / genetics*
  • CpG Islands
  • DNA Methylation
  • DNA, Neoplasm / genetics*
  • Humans

Substances

  • DNA, Neoplasm