COP sets TRAPP for vesicles

Alexander K Haas; Francis A Barr

doi:10.1016/j.devcel.2007.02.001

COP sets TRAPP for vesicles

Dev Cell. 2007 Mar;12(3):326-7. doi: 10.1016/j.devcel.2007.02.001.

Authors

Alexander K Haas¹, Francis A Barr

Affiliation

¹ Department of Cell Biology, Max-Planck-Institute of Biochemistry, Martinsried 82152, Germany.

PMID: 17336899
DOI: 10.1016/j.devcel.2007.02.001

Abstract

Intracellular transport vesicles identify their destination by a poorly understood process termed tethering. Recent work shows that in addition to its role in membrane-cargo selection, the COPII vesicle coat recruits TRAPPI, a cytosolic protein complex required for vesicle tethering.

MeSH terms

Animals
COP-Coated Vesicles / metabolism*
Endoplasmic Reticulum / metabolism
Endoplasmic Reticulum / ultrastructure
Golgi Apparatus / metabolism
Golgi Apparatus / ultrastructure
Humans
Intracellular Membranes / metabolism*
Intracellular Membranes / ultrastructure
Membrane Proteins / metabolism*
Signal Transduction / physiology
Transport Vesicles / metabolism*
Transport Vesicles / ultrastructure
Vesicular Transport Proteins / metabolism*
Yeasts / metabolism
rab GTP-Binding Proteins / metabolism*

Substances

Membrane Proteins
Vesicular Transport Proteins
transport protein particle, TRAPP
rab GTP-Binding Proteins