Antimicrobial and cytotoxic activities of Achyranthes ferruginea

M Mukhlesur Rahman; A H M Khurshid Alam; Golam Sadik; M Robiul Islam; Proma Khondkar; M Aslam Hossain; Mohammad A Rashid

doi:10.1016/j.fitote.2006.12.003

Antimicrobial and cytotoxic activities of Achyranthes ferruginea

Fitoterapia. 2007 Apr;78(3):260-2. doi: 10.1016/j.fitote.2006.12.003. Epub 2007 Feb 6.

Authors

M Mukhlesur Rahman¹, A H M Khurshid Alam, Golam Sadik, M Robiul Islam, Proma Khondkar, M Aslam Hossain, Mohammad A Rashid

Affiliation

¹ Phytochemistry Research Laboratories, Department of Pharmacy, University of Rajshahi, Rajshahi-6205, Bangladesh. mukhlesurrah@yahoo.co.uk

PMID: 17335997
DOI: 10.1016/j.fitote.2006.12.003

Abstract

Chloroform extract (CE) of Achyranthes ferruginea and N-trans-feruloyl-4-methyldopamine (1) showed remarkable antimicrobial activities against a wide range of bacteria and fungi. Both crude extract (CE) and compound 1 showed significant cytotoxicity of LC(50) at 16.21 microg/ml and 11.70 microg/ml, respectively.

MeSH terms

Achyranthes*
Anti-Bacterial Agents / administration & dosage
Anti-Bacterial Agents / pharmacology*
Anti-Bacterial Agents / therapeutic use
Antifungal Agents / administration & dosage
Antifungal Agents / pharmacology*
Antifungal Agents / therapeutic use
Gram-Negative Bacteria / drug effects
Gram-Positive Bacteria / drug effects
Humans
Microbial Sensitivity Tests
Mitosporic Fungi / drug effects
Phytotherapy*
Plant Extracts / administration & dosage
Plant Extracts / pharmacology*
Plant Extracts / therapeutic use

Substances

Anti-Bacterial Agents
Antifungal Agents
Plant Extracts