One-year postoperative autobiographical memory following unilateral temporal lobectomy for control of intractable epilepsy

Epilepsia. 2007 Mar;48(3):605-8. doi: 10.1111/j.1528-1167.2006.00970.x. Epub 2007 Feb 22.

Abstract

Purpose: To examine the effects of temporal lobectomy (TL), particularly concerning its lateralization.

Methods: Patients completed autobiographical memory tests, preoperatively and 1-year postoperatively.

Results: (a) right TL (RTL) patients recalled significantly more memories from the year after surgery than from the year before TL; (b) their pre to postoperative improvement on autobiographical memory scores was positively correlated to improvement of delayed story recall scores; and (c) 1 year after surgery, performance on recent personal memory recall was normalized for RTL patients only.

Conclusion: We suggest that, in the absence of recurrent seizures, the relative integrity of the left hemisphere together with residual right hemisphere structures sustains postoperative autobiographical memory consolidation, at least 1 year postoperatively.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Anterior Temporal Lobectomy*
  • Epilepsy, Temporal Lobe / diagnosis
  • Epilepsy, Temporal Lobe / physiopathology*
  • Epilepsy, Temporal Lobe / surgery*
  • Female
  • Functional Laterality / physiology*
  • Humans
  • Male
  • Memory / physiology*
  • Mental Recall / physiology
  • Neuropsychological Tests / standards*
  • Neuropsychological Tests / statistics & numerical data*
  • Postoperative Period*
  • Recurrence
  • Temporal Lobe / physiology
  • Temporal Lobe / physiopathology
  • Treatment Outcome