Genetic data of 10 X-STRs in a Spanish population sample

M Aler; P Sánchez-Diz; I Gomes; M Gisbert; A Carracedo; A Amorim; L Gusmão

doi:10.1016/j.forsciint.2006.10.023

Genetic data of 10 X-STRs in a Spanish population sample

Forensic Sci Int. 2007 Dec 20;173(2-3):193-6. doi: 10.1016/j.forsciint.2006.10.023. Epub 2007 Feb 22.

Authors

M Aler¹, P Sánchez-Diz, I Gomes, M Gisbert, A Carracedo, A Amorim, L Gusmão

Affiliation

¹ Forensic Genetics U.D. Legal Medicine, University of Valencia E.G., Valencia, Spain.

PMID: 17320320
DOI: 10.1016/j.forsciint.2006.10.023

Abstract

In this work, we present population genetic data of 10 X-chromosome STRs (DXS8378, DXS9898, DXS8377, HPRTB, GATA172D05, DXS7423, DXS6809, DXS7132, DXS101 and DXS6789) obtained from sample of 145 unrelated female individuals belonging to Valencia (Spain), a region located in the east of the Iberian Peninsula. All the markers studied present high genetic diversities, similar to those previously reported in other European population samples. No deviations from Hardy-Weinberg equilibrium were observed, with the exception of DXS101 locus. Allele frequencies and parameters of forensic interest for each X-STR were calculated. High mean exclusion chance and power of discrimination values were obtained by combining these 10 X-linked markers. Population comparisons (exact test of population differentiation; pairwise genetic distances) were carried out and low genetic distances were found between our sample and those from other Spanish or European regions.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Chromosomes, Human, X*
DNA Fingerprinting
Female
Gene Frequency
Genetics, Population*
Humans
Polymerase Chain Reaction
Spain
Tandem Repeat Sequences*