[Monitoring of resistance to chemotherapeutics of enterobacteria strains isolated from urocultures from out-patients]

Bacteriol Virusol Parazitol Epidemiol. 2005 Jan-Jun;50(1-2):49-57.
[Article in Romanian]

Abstract

The importance of urinary tract infections relies in their relatively high incidence, as well as in their numerous and complicated problems of diagnosis and treatment. Considering the high incidence of urinary infections we made a study in order to determine the antibiotic susceptibility of Enterobacteriaceae strains isolated from urocultures of ambulatory patients and to precise the resistance phenotypes of these strains. We studied enterobacteriaceae strains isolated from 1889 urocultures of ambulatory patients between January - December 2004. From 1889 urocultures 431 were positive, the most common strains were E. coli - 350 strains (81.21%). We observed a constant lowering of the sensitivity of E. coli strains to many antimicrobial agents which draws attention to on the importance of monitoring antibiotics prescriptions. We must draw a signal about the presence of some ESBL (beta-lactamase with extended spectrum) strains (1 E. coli strain and 3 Klebsiella pneumoniae strains), which are usually isolated in hospital, due to empiric, irrational and abusive usage of antibiotics, without doing the antibiograms.

MeSH terms

  • Adolescent
  • Adult
  • Anti-Bacterial Agents / pharmacology*
  • Anti-Bacterial Agents / therapeutic use
  • Child
  • Child, Preschool
  • Drug Resistance, Multiple, Bacterial*
  • Enterobacteriaceae / drug effects*
  • Enterobacteriaceae / genetics
  • Enterobacteriaceae Infections / drug therapy
  • Enterobacteriaceae Infections / microbiology*
  • Escherichia coli / drug effects
  • Female
  • Humans
  • Infant
  • Infant, Newborn
  • Klebsiella pneumoniae / drug effects
  • Male
  • Microbial Sensitivity Tests / methods
  • Middle Aged
  • Outpatients
  • Phenotype
  • Retrospective Studies
  • Urinary Tract Infections / drug therapy
  • Urinary Tract Infections / microbiology*
  • Urine / microbiology*
  • beta-Lactam Resistance

Substances

  • Anti-Bacterial Agents