Synthesis of 1,3,5-tricarbonyl derivatives by condensation of 1,3-bis(silyl enol ethers) with acid chlorides

Thomas Rahn; Van T H Nguyen; T H Tam Dang; Zafar Ahmed; Karen Methling; Michael Lalk; Christine Fischer; Anke Spannenberg; Peter Langer

doi:10.1021/jo062153w

Synthesis of 1,3,5-tricarbonyl derivatives by condensation of 1,3-bis(silyl enol ethers) with acid chlorides

J Org Chem. 2007 Mar 16;72(6):1957-61. doi: 10.1021/jo062153w. Epub 2007 Feb 8.

Authors

Thomas Rahn¹, Van T H Nguyen, T H Tam Dang, Zafar Ahmed, Karen Methling, Michael Lalk, Christine Fischer, Anke Spannenberg, Peter Langer

Affiliation

¹ Institut für Chemie, Universität Rostock, Albert-Einstein-Strasse 3a, 18059 Rostock, Germany.

PMID: 17286437
DOI: 10.1021/jo062153w

Abstract

A variety of 1,3,5-tricarbonyl derivatives were prepared by reaction of 1,3-bis(silyl enol ethers) with acid chlorides under mild conditions. This includes reactions of both aromatic and aliphatic acid chlorides and bis(acid chlorides). The yields vary depending on the type of acid chloride employed.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Acids / chemistry
Ether / chemistry*
Organometallic Compounds / chemical synthesis
Silanes / chemistry*

Substances

Acids
Organometallic Compounds
Silanes
Ether