Computer-assisted design/computer-assisted manufacturing (CAD/CAM) has been used successfully in commercial industry for several decades and is only now becoming more common for use within the clinical setting. This presentation will outline how CAD/CAM frameworks present numerous advantages over conventional castings when used to treat edentulous and partially edentulous patients in such areas as strength, biocompatibility, and precision machining. Recent advancements in CAD/CAM technology have decreased the costs associated with the fabrication of implant- and tooth-borne frameworks.