Dissemination of sul3-containing elements linked to class 1 integrons with an unusual 3' conserved sequence region among Salmonella isolates

Antimicrob Agents Chemother. 2007 Apr;51(4):1545-8. doi: 10.1128/AAC.01275-06. Epub 2007 Feb 5.

Abstract

A sul3 domain (IS440-sul3-orf1-IS26) was found linked to an unusual 3' conserved sequence region (qacH) of class 1 integrons and detected among nontyphoid Salmonella isolates (n=47) from different sources. Three types of integrons differing in the gene cassette array (dfrA12-orfF-aadA2-cmlA1-aadA1, dfrA12-orfF-aadA2/1, and estX-psp-aadA2-cmlA1-aadA1) were found associated with this sul3 domain. They were associated with particular clones and specific high-molecular-weight plasmids.

MeSH terms

  • Bacterial Proteins / genetics*
  • Conserved Sequence*
  • DNA, Bacterial / chemistry*
  • Integrons / genetics*
  • Molecular Sequence Data
  • Plasmids / genetics
  • Salmonella / classification
  • Salmonella / genetics*
  • Salmonella / isolation & purification

Substances

  • Bacterial Proteins
  • DNA, Bacterial
  • Sul3 protein, Salmonella enterica

Associated data

  • GENBANK/EF051037
  • GENBANK/EF051038
  • GENBANK/EF051039