Sequential acquisition and processing of perfusion and diffusion MRI data for a porcine stroke model

Matthew A Neimark; Andrew F Laine; Erwin Lin; Stephen Dashnaw; John Pile-Spellman

doi:10.1109/IEMBS.2005.1615802

Sequential acquisition and processing of perfusion and diffusion MRI data for a porcine stroke model

Conf Proc IEEE Eng Med Biol Soc. 2005:2005:5782-5. doi: 10.1109/IEMBS.2005.1615802.

Authors

Matthew A Neimark¹, Andrew F Laine, Erwin Lin, Stephen Dashnaw, John Pile-Spellman

Affiliation

¹ Department of Biomedical Engineering, Columbia University, New York, NY, USA.

PMID: 17281572
DOI: 10.1109/IEMBS.2005.1615802

Abstract

An automated data processing pipeline, designed for handling a large throughput of sequentially acquired MRI brain data, is described. The system takes as input multiple diffusion weighted (DWI) and perfusion weighted imaging (PWI) volumes acquired at different temporal points, automatically segments and registers them, and ultimately outputs a database used to track various perfusion and diffusion parameters through time at individual brain voxels. This pipeline has been utilized to successfully process two pig brains from an induced stroke experiment.