Photodynamic treatment of cutaneous leishmaniasis

J Dtsch Dermatol Ges. 2007 Feb;5(2):128-30. doi: 10.1111/j.1610-0387.2007.06177.x.
[Article in English, German]

Abstract

Leishmaniasis is a widespread arthropod-borne protozoan zoonosis caused by more than 21 Leishmania species. Vectors are sandflies of different genera. The disease is classified into "Old World" versus "New World" leishmaniasis and further subclassified in cutaneous, mucocutaneous and visceral forms. Most therapeutic approaches are not evidence-based. We report a patient with facial cutaneous Leishmania tropica infection which proved to be resistant to various therapeutic regimes. Excellent results were achieved with photodynamic therapy.

Publication types

  • Case Reports

MeSH terms

  • Aminolevulinic Acid / analogs & derivatives*
  • Aminolevulinic Acid / therapeutic use
  • Humans
  • Leishmaniasis, Diffuse Cutaneous / drug therapy*
  • Leishmaniasis, Diffuse Cutaneous / pathology*
  • Male
  • Middle Aged
  • Photochemotherapy / methods*
  • Photosensitizing Agents / therapeutic use
  • Treatment Outcome

Substances

  • Photosensitizing Agents
  • methyl 5-aminolevulinate
  • Aminolevulinic Acid