Anti-tobacco mosaic virus (TMV) triterpenoid saponins from the leaves of Ilex oblonga

J Agric Food Chem. 2007 Mar 7;55(5):1712-7. doi: 10.1021/jf062421r. Epub 2007 Feb 3.

Abstract

Ten triterpene saponins have been isolated from a MeOH extract of the leaves of Ilex oblonga. In their structures, six new triterpenoid saponins were named as oblonganosides H-M (2, 4, 5, and 8-10). All structures were elucidated on the basis of spectroscopic analysis. Among the triterpenoid saponins, three compounds (7, 8, and 10) showed obvious activities in inhibiting multiplication of the tobacco mosaic virus (TMV).

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antiviral Agents / isolation & purification*
  • Antiviral Agents / pharmacology
  • Ilex / chemistry*
  • Plant Extracts / chemistry
  • Plant Leaves / chemistry*
  • Saponins / isolation & purification*
  • Saponins / pharmacology
  • Tobacco Mosaic Virus / drug effects*
  • Triterpenes / isolation & purification*
  • Triterpenes / pharmacology

Substances

  • Antiviral Agents
  • Plant Extracts
  • Saponins
  • Triterpenes