From the aerial parts of Euphorbia iberica, an ingenane diterpene ester, ingenol 20-eicosanoate, and three ursanetype triterpenoids, 3beta-acetoxy-urs-12-ene-1beta,11alpha-diol, 3beta-( E)-coumaroyloxy-urs-12-ene, and 3beta-( Z)-coumaroyloxy-urs-12-ene have been isolated together with known cylcoartane-type triterpenes, a flavone, and coumarins. The first four compounds are new and their structures were determined by spectroscopic methods.