Ferulsinaic acid, a sesquiterpene coumarin with a rare carbon skeleton from Ferula species

Ahmed A Ahmed; Mohamed-Elamir F Hegazy; Amar Zellagui; Salah Rhouati; Tarik A Mohamed; Ahmed A Sayed; Mohamed A Abdella; Shinji Ohta; Toshifumi Hirata

doi:10.1016/j.phytochem.2006.12.011

Ferulsinaic acid, a sesquiterpene coumarin with a rare carbon skeleton from Ferula species

Phytochemistry. 2007 Mar;68(5):680-6. doi: 10.1016/j.phytochem.2006.12.011. Epub 2007 Jan 26.

Authors

Ahmed A Ahmed¹, Mohamed-Elamir F Hegazy, Amar Zellagui, Salah Rhouati, Tarik A Mohamed, Ahmed A Sayed, Mohamed A Abdella, Shinji Ohta, Toshifumi Hirata

Affiliation

¹ Department of Chemistry, El-Minia University, El-Minia 61519, Egypt.

PMID: 17258243
DOI: 10.1016/j.phytochem.2006.12.011

Abstract

Fractionation of methylene chloride extracts of the resin of Ferula vesceritensis and F. sinaica afforded three sesquiterpene coumarins and a glucose derivative. One of them was a sesquiterpene with a rare carbon skeleton. The structures of these compounds were determined by extensive NMR studies, including DEPT, COSY, NOE, HMQC, and HMBC.

MeSH terms

Coumarins / chemistry*
Coumarins / isolation & purification
Ferula / chemistry*
Magnetic Resonance Spectroscopy / methods
Models, Molecular
Molecular Conformation
Plant Extracts / chemistry*
Plant Extracts / isolation & purification
Plant Roots / chemistry*
Sesquiterpenes / chemistry*
Sesquiterpenes / isolation & purification

Substances

Coumarins
Plant Extracts
Sesquiterpenes
ferulsinaic acid