Heavy tools for genome mining

Chem Biol. 2007 Jan;14(1):7-9. doi: 10.1016/j.chembiol.2007.01.001.

Abstract

In this issue of Chemistry & Biology, Gross et al. report development of a novel genome mining method for isolating products of orphan biosynthetic gene clusters, and the application of this method to the isolation of orfamide A, a novel cyclic lipopeptide.

Publication types

  • Comment

MeSH terms

  • Biological Products / isolation & purification
  • Computational Biology / methods*
  • Genomics / methods*
  • Lipoproteins / isolation & purification
  • Peptides, Cyclic / isolation & purification

Substances

  • Biological Products
  • Lipoproteins
  • Peptides, Cyclic