Acute mastoiditis: increase of incidence and controversies in antibiotic treatment

Rev Esp Quimioter. 2006 Dec;19(4):337-41.

Abstract

An important complication of acute otitis media is acute mastoiditis which responds to antibiotic therapy and myringotomy. Patients with acute mastoiditis were reviewed during 1996-2005 in the tertiary University Children's Hospital in Madrid. The number of patients with acute mastoiditis increased by about 2-fold during this period. Of 205 children with mastoiditis, ranging from 0.6-17 years of age, surgical treatment was needed in about 4.3% in 1996 and in 70% in 2005. In spite of 80% of the children having received antibiotics at the pediatric visit, the number of complications increased (periostitis, subperiosteal abscess), and the number of surgical interventions increased by 8-fold. Etiological agents were Streptococcus pneumoniae (28.5%) and Staphylococcus aureus (16.3%). Negative cultures were obtained in 53.6% of cases. Lack of response to conventional therapy may require more tympanocentesis procedures for a middle ear culture, and surgical therapy may be necessary more often, as is the tendency in our hospital.

MeSH terms

  • Abscess / epidemiology
  • Abscess / etiology
  • Abscess / prevention & control
  • Acute Disease
  • Adolescent
  • Anti-Bacterial Agents / administration & dosage
  • Anti-Bacterial Agents / therapeutic use*
  • Child
  • Child, Preschool
  • Combined Modality Therapy
  • Contraindications
  • Drug Resistance
  • Drug Utilization / standards
  • Drug Utilization / statistics & numerical data
  • Female
  • Gram-Negative Bacterial Infections / drug therapy
  • Gram-Negative Bacterial Infections / epidemiology
  • Gram-Negative Bacterial Infections / microbiology
  • Gram-Negative Bacterial Infections / surgery
  • Gram-Positive Bacterial Infections / drug therapy
  • Gram-Positive Bacterial Infections / epidemiology
  • Gram-Positive Bacterial Infections / microbiology
  • Gram-Positive Bacterial Infections / surgery
  • Humans
  • Incidence
  • Infant
  • Male
  • Mastoiditis / complications
  • Mastoiditis / diagnosis
  • Mastoiditis / drug therapy
  • Mastoiditis / epidemiology*
  • Mastoiditis / surgery
  • Meningoencephalitis / etiology
  • Meningoencephalitis / prevention & control
  • Otitis Media / complications
  • Periostitis / epidemiology
  • Periostitis / etiology
  • Periostitis / prevention & control
  • Respiratory Tract Infections / complications
  • Respiratory Tract Infections / drug therapy
  • Respiratory Tract Infections / epidemiology
  • Respiratory Tract Infections / microbiology
  • Respiratory Tract Infections / virology
  • Retrospective Studies
  • Risk
  • Spain / epidemiology
  • Treatment Outcome

Substances

  • Anti-Bacterial Agents