Coating urinary catheters with an avirulent strain of Escherichia coli as a means to establish asymptomatic colonization

Infect Control Hosp Epidemiol. 2007 Jan;28(1):92-4. doi: 10.1086/510872. Epub 2006 Dec 29.

Abstract

We investigated whether insertion of urinary catheters that had been coated with Escherichia coli HU2117 could establish bladder colonization with this nonvirulent organism. Ten of 12 subjects were successfully colonized for 14 days or more. The rate of symptomatic UTI during colonization was 0.15 per 100 patient-days.

Publication types

  • Clinical Trial
  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Catheters, Indwelling / microbiology*
  • Child
  • Escherichia coli / growth & development*
  • Female
  • Humans
  • Urinary Bladder, Neurogenic / microbiology*
  • Urinary Catheterization*
  • Urinary Tract Infections / epidemiology
  • Urinary Tract Infections / prevention & control*