Photopatterning of polybutadiene substrates by interferometric ultraviolet lithography: fabrication of phospholipid microarrays

Appl Opt. 2007 Feb 1;46(4):489-94. doi: 10.1364/ao.46.000489.

Abstract

Gratings are written holographically with low power (10 mW/cm(2)) 244 nm UV light on thin films of polybutadiene rubber polymer. The increase of hydrophilicity-wettability of polybutadiene films is measured over UV-exposed regions. Sequential fabrication of two orthogonal gratings results in hydrophilic microarrays having applications as functionalized substrates for immobilizing biomolecules. This is demonstrated by immobilizing a phospholipid in a microarray pattern.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Butadienes / chemistry*
  • Chloroform
  • Elastomers / chemistry*
  • Microfluidic Analytical Techniques*
  • Microscopy, Atomic Force
  • Nickel / chemistry
  • Optics and Photonics*
  • Phospholipids / chemistry*
  • Polymers / chemistry*
  • Printing / methods*
  • Proteins / chemistry
  • Solvents / chemistry
  • Surface Properties
  • Time Factors
  • Ultraviolet Rays

Substances

  • Butadienes
  • Elastomers
  • Phospholipids
  • Polymers
  • Proteins
  • Solvents
  • Nickel
  • Chloroform
  • polybutadiene