Simple but effective way to sense pyrophosphate and inorganic phosphate by fluorescence changes

Org Lett. 2007 Jan 18;9(2):243-6. doi: 10.1021/ol062685z.

Abstract

A new fluorescent chemosensor based on the acridine-Zn(II) derivative effectively recognizes pyrophosphate and inorganic phosphate at pH 7.4. Acridine derivative 1 displayed a fluorescent quenching effect with pyrophosphate; on the other hand, a large fluorescent enhancement was observed with inorganic phosphate. [structure: see text].

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acridines / chemistry*
  • Crystallography, X-Ray
  • Diphosphates / analysis*
  • Diphosphates / chemistry
  • Fluorescence
  • Hydrogen-Ion Concentration
  • Models, Molecular
  • Molecular Structure
  • Organometallic Compounds / chemical synthesis
  • Organometallic Compounds / chemistry*
  • Phosphates / analysis*
  • Phosphates / chemistry
  • Sensitivity and Specificity
  • Titrimetry / methods
  • Zinc / chemistry*

Substances

  • Acridines
  • Diphosphates
  • Organometallic Compounds
  • Phosphates
  • Zinc