Enantiopure pseudo-C3-symmetric titanium alkoxide with propeller-like chirality

Philip Axe; Steven D Bull; Matthew G Davidson; Carly J Gilfillan; Matthew D Jones; Diane E J E Robinson; Luke E Turner; William L Mitchell

doi:10.1021/ol062655w

Enantiopure pseudo-C3-symmetric titanium alkoxide with propeller-like chirality

Org Lett. 2007 Jan 18;9(2):223-6. doi: 10.1021/ol062655w.

Authors

Philip Axe¹, Steven D Bull, Matthew G Davidson, Carly J Gilfillan, Matthew D Jones, Diane E J E Robinson, Luke E Turner, William L Mitchell

Affiliation

¹ Department of Chemistry, University of Bath, Claverton Down, Bath, BA2 7AY, UK.

PMID: 17217270
DOI: 10.1021/ol062655w

Abstract

An enantiopure amine tris(phenolate) ligand containing a single stereogenic center has been used to control the propeller-like chirality of a derived pseudo-C3-symmetric titanium isopropoxide complex with excellent levels of diastereocontrol. [structure: see text].

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Crystallography, X-Ray
Ligands
Magnetic Resonance Spectroscopy / methods
Models, Molecular
Molecular Structure
Organometallic Compounds / chemistry*
Sensitivity and Specificity
Stereoisomerism
Titanium / chemistry*

Substances

Ligands
Organometallic Compounds
Titanium