Motor inhibition in trichotillomania and obsessive-compulsive disorder

Antje Bohne; Cary R Savage; Thilo Deckersbach; Nancy J Keuthen; Sabine Wilhelm

doi:10.1016/j.jpsychires.2006.11.008

Motor inhibition in trichotillomania and obsessive-compulsive disorder

J Psychiatr Res. 2008 Jan;42(2):141-50. doi: 10.1016/j.jpsychires.2006.11.008. Epub 2007 Jan 9.

Authors

Antje Bohne¹, Cary R Savage, Thilo Deckersbach, Nancy J Keuthen, Sabine Wilhelm

Affiliation

¹ Massachusetts General Hospital/Harvard Medical School, OCD Clinic, Simches Research Building, 2nd Floor, 185 Cambridge Street, Boston, MA 02114, USA.

PMID: 17215004
DOI: 10.1016/j.jpsychires.2006.11.008

Abstract

We investigated motor inhibition abilities in trichotillomania (TTM) and obsessive-compulsive disorder (OCD), two disorders characterized by repetitive, intentionally performed behaviors. Performance in a GoNogo experiment of 25 TTM and 21 OCD participants was compared to the performance of 26 HC participants. In contrast to OCD and HC participants, TTM participants tended to perform either 'fast and inaccurate' (indicating poor motor inhibition) or 'slow and accurate'. TTM participants with poor motor inhibition reported a significantly earlier age of TTM onset than those TTM participants who performed well. There was no evidence for motor inhibition deficits in OCD. Based on our data, a subgroup of TTM sufferers seems to be characterized by motor inhibition deficits.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Adult
Attention
Cues
Female
Humans
Impulsive Behavior / diagnosis
Impulsive Behavior / psychology
Inhibition, Psychological*
Male
Middle Aged
Neuropsychological Tests
Obsessive-Compulsive Disorder / diagnosis
Obsessive-Compulsive Disorder / psychology*
Pattern Recognition, Visual
Psychomotor Performance*
Reaction Time
Stereotyped Behavior
Trichotillomania / diagnosis
Trichotillomania / psychology*