Adherence to guidelines for patients hospitalized with heart failure: a nationwide survey

Isr Med Assoc J. 2006 Dec;8(12):875-9.

Abstract

Background: Despite significant advances in the therapy of heart failure, many patients still do not receive optimal treatment.

Objectives: To document the standard of care that patients hospitalized with HF in Israel received during a 2 month period.

Methods: The Heart Failure Survey in Israel 2003 was a prospective 2 month survey of patients admitted to all 25 public hospitals in Israel with a diagnosis of HF.

Results: The mean age of the 4102 patients was 73 years and 43% were female. The use of angiotensin-converting enzyme/angiotensin receptor blockers and beta blockers both declined from NYHA class I to IV (68.8% to 50.6% for ACE-inhibitor/ARB and 64.1% to 52.9% for beta blockers, P < 0.001 for comparisons). The percentage of patients by NYHA class taking an ACE-inhibitor or ARB and a beta blocker at hospital discharge also declined from NYHA class I to IV (47.5% to 28.8%, P < 0.002 for comparisons). The strongest predictor of being discharged with an ACE-inhibitor or ARB was the use of these medications at hospital admission. Negative predictors for their usage were age, creatinine, disease severity class, and functional status.

Conclusions: Despite the dissemination of guidelines many patients did not receive optimal care for HF. Reasons for this discrepancy need to be identified and modified.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adrenergic beta-Antagonists / therapeutic use*
  • Aged
  • Aged, 80 and over
  • Angiotensin-Converting Enzyme Inhibitors / therapeutic use*
  • Calcium Channel Blockers / therapeutic use
  • Diuretics / therapeutic use
  • Drug Utilization Review*
  • Female
  • Guideline Adherence / statistics & numerical data*
  • Health Care Surveys
  • Heart Failure / drug therapy*
  • Heart Failure / physiopathology
  • Hospitals, Public / standards*
  • Humans
  • Israel
  • Male
  • Middle Aged
  • Mineralocorticoid Receptor Antagonists / therapeutic use
  • Myocardial Ischemia / drug therapy
  • Myocardial Ischemia / physiopathology
  • Patient Admission
  • Patient Discharge
  • Practice Guidelines as Topic*
  • Prospective Studies
  • Quality of Health Care*
  • Spironolactone / therapeutic use

Substances

  • Adrenergic beta-Antagonists
  • Angiotensin-Converting Enzyme Inhibitors
  • Calcium Channel Blockers
  • Diuretics
  • Mineralocorticoid Receptor Antagonists
  • Spironolactone