Clinical utility of HIV standard genotyping among antiretroviral-naive individuals with unknown duration of infection

Clin Infect Dis. 2007 Feb 1;44(3):456-8. doi: 10.1086/510748. Epub 2006 Dec 28.

Abstract

In clinical settings, we have found a high rate of human immunodeficiency virus (HIV) drug resistance among antiretroviral-naive patients for whom the duration of infection was unknown. These high rates were most likely the result of both transmitted resistance and informal antiretroviral use, and they suggest that routine resistance testing among antiretroviral-naive patients would be a cost-effective clinical practice.

Publication types

  • Multicenter Study
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Anti-HIV Agents / pharmacology*
  • California / epidemiology
  • Drug Resistance, Multiple, Viral / drug effects
  • Drug Resistance, Multiple, Viral / genetics*
  • Female
  • Genotype
  • HIV / drug effects*
  • HIV / genetics
  • HIV Infections / drug therapy*
  • HIV Infections / genetics
  • Humans
  • Male
  • Patient Care Planning
  • Prevalence
  • Treatment Outcome

Substances

  • Anti-HIV Agents