CT diagnosis of 52 patients with lymphoma in abdominal lymph nodes

World J Gastroenterol. 2006 Dec 28;12(48):7869-73. doi: 10.3748/wjg.v12.i48.7869.

Abstract

Aim: To assess CT manifestations and its diagnostic value for lymphoma in the abdominal lymph nodes (LALN).

Methods: CT findings in 52 cases of LALN proved by surgery or biopsy, including Hodgkin's disease (HD) in 16 cases and non-Hodgkin's lymphoma (NHL) in 36 cases, were retrospectively analyzed.

Results: (1) CT manifestations based on distribution of the lesions of LALN: Solitary mass type was found in 10 cases, including solitary, round, uniform-density, enlarged lymph nodes in 3 cases; and multiple, enlarged lymph nodes fusing into singular lobular mass in 7 cases. Thirty-four cases of multiple-nodular type showed multiple, round, enlarged lymph nodes with uniform density and clear margins. Vessels-embedded signs, including mesenteric vessels, renal vessels, abdominal aorta or inferior vena cava, were seen in 6 cases, and duodenum-embedded signs were seen in 2 cases. Eight cases of diffuse type showed characteristic "cobblestone signs". (2) CT manifestations correlated with pathological type: CT manifestations of 12 cases of HD were different from those of 40 cases of NHL in distribution, size, quantity and fused lesion of enlarged lymph nodes. (3) Twenty-eight cases of 52 patients were accompanied with extra-nodal lymphoma in the abdomen, especially gastrointestinal lymphoma, which had characteristic CT findings. (4) In follow-up examinations, CT images showed uniform, heterogeneous or rim enhancement in 15 cases, and occasional calcifications accompanied with reduction of the lesion size and quantity in 12 cases, whereas the lesions disappeared in 3 cases after treatment.

Conclusion: CT images show many characteristic manifestations valuable for qualitative diagnosis of LALN, and it is also helpful for pathological classification of LALN and therapeutic evaluation in follow-up of patients.

Publication types

  • Evaluation Study

MeSH terms

  • Abdomen
  • Adolescent
  • Adult
  • Aged
  • Diagnosis, Differential
  • Female
  • Hodgkin Disease / diagnostic imaging*
  • Hodgkin Disease / pathology*
  • Hodgkin Disease / therapy
  • Humans
  • Intestines / pathology
  • Kidney / pathology
  • Lymph Nodes / pathology*
  • Lymphoma, Non-Hodgkin / diagnostic imaging*
  • Lymphoma, Non-Hodgkin / pathology*
  • Lymphoma, Non-Hodgkin / therapy
  • Male
  • Middle Aged
  • Retrospective Studies
  • Sensitivity and Specificity
  • Stomach / pathology
  • Tomography, X-Ray Computed / methods*