Abstract
Heterotrimeric G-protein complexes couple extracellular signals via cell surface receptors to downstream enzymes called effectors. Heterotrimeric G-protein complexes, together with their cognate receptors and effectors, operate at the apex of signal transduction. In plants, the number of G-protein complex components is dramatically less than in other multicellular eukaryotes. An understanding of how multiple signals propagate transduction through the G-protein node can be found in the unique structural and kinetic properties of the plant heterotrimeric G-protein complex. This review addresses these unique features and speculates on why the repertoire of G-protein signaling elements is dramatically simpler than that in all other multicellular eukaryotes.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, U.S. Gov't, Non-P.H.S.
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Review
MeSH terms
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Amino Acid Sequence
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Arabidopsis / metabolism
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Arabidopsis Proteins / metabolism
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Heterotrimeric GTP-Binding Proteins / chemistry
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Heterotrimeric GTP-Binding Proteins / metabolism
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Heterotrimeric GTP-Binding Proteins / physiology*
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Kinetics
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Models, Biological
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Models, Molecular
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Molecular Sequence Data
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Plant Proteins / chemistry
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Plant Proteins / metabolism
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Plant Proteins / physiology*
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Protein Structure, Quaternary
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Protein Subunits / chemistry
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Protein Subunits / metabolism
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Protein Subunits / physiology
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RGS Proteins / metabolism
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Signal Transduction
Substances
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Arabidopsis Proteins
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Plant Proteins
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Protein Subunits
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RGS Proteins
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RGS1 protein, Arabidopsis
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Heterotrimeric GTP-Binding Proteins