Background and purpose: Insular cortex ischemia is proposed to mediate a sympathetic stimulus that leads to acute hyperglycemia after stroke.
Methods: We retrospectively analyzed insular perfusion on perfusion CT (median 180 minutes after onset) in 35 patients.
Results: We found no association of hypoperfusion (relative cerebral blood flow <0.51) with early (<6 hours) or delayed (<72 hours) hyperglycemia, or hemispheric lateralization.
Conclusions: Insular cortex hypoperfusion <6 hours after stroke onset was not associated with hyperglycemia.