Immune reconstitution inflammatory syndrome presenting as sinusitis with inflammatory pseudotumor in an HIV-infected patient: a case report and review of the literature

Kirk M Chan-Tack; K Savitha Chengappa; Jeffrey S Wolf; Grace F Kao; Ronald B Reisler

doi:10.1089/apc.2006.20.823

Immune reconstitution inflammatory syndrome presenting as sinusitis with inflammatory pseudotumor in an HIV-infected patient: a case report and review of the literature

AIDS Patient Care STDS. 2006 Dec;20(12):823-8. doi: 10.1089/apc.2006.20.823.

Authors

Kirk M Chan-Tack¹, K Savitha Chengappa, Jeffrey S Wolf, Grace F Kao, Ronald B Reisler

Affiliation

¹ Institute of Human Virology, University of Maryland School of Medicine, 725 West Lombard Street, UMBI, N540, Baltimore, Maryland 21201, USA. kchan@medicine.umaryland.edu

PMID: 17192147
DOI: 10.1089/apc.2006.20.823

Abstract

Immune reconstitution inflammatory syndrome (IRIS) encompasses a variety of conditions that occur among HIV-infected patients in a temporal relationship with increases in CD4 cell count as a result of highly active antiretroviral therapy (HAART). Most conditions associated with IRIS are infectious. Malignancies, such as Kaposi's sarcoma, have also been reported. We report a case of sinusitis with presumptive inflammatory pseudotumor as a manifestation of IRIS that occurred 20 weeks after the initiation of HAART.

Publication types

Case Reports
Research Support, Non-U.S. Gov't
Review

MeSH terms

AIDS-Related Opportunistic Infections / pathology*
Adult
Antiretroviral Therapy, Highly Active / adverse effects*
CD4 Lymphocyte Count
Granuloma, Plasma Cell / complications
Granuloma, Plasma Cell / physiopathology*
HIV Infections / drug therapy*
Humans
Male
Sinusitis / chemically induced*
Sinusitis / diagnosis
Sinusitis / pathology