Cationic palladium complex catalyzed highly enantioselective intramolecular addition of arylboronic acids to ketones. A convenient synthesis of optically active cycloalkanols

Guixia Liu; Xiyan Lu

doi:10.1021/ja0672425

Cationic palladium complex catalyzed highly enantioselective intramolecular addition of arylboronic acids to ketones. A convenient synthesis of optically active cycloalkanols

J Am Chem Soc. 2006 Dec 27;128(51):16504-5. doi: 10.1021/ja0672425.

Authors

Guixia Liu¹, Xiyan Lu

Affiliation

¹ State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 354 Fenglin Lu, Shanghai 200032, China.

PMID: 17177391
DOI: 10.1021/ja0672425

Abstract

An efficient and convenient synthesis of optically active cycloalkanols by utilizing the chiral cationic palladium complex as the catalyst was achieved in mild conditions with high yield and high enantioselectivity.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Acetylation
Alcohols / chemical synthesis*
Alcohols / chemistry
Boronic Acids / chemistry*
Catalysis
Cations / chemistry
Cyclization
Ketones / chemistry*
Molecular Structure
Optical Rotation
Organometallic Compounds / chemistry*
Palladium / chemistry*
Stereoisomerism

Substances

Alcohols
Boronic Acids
Cations
Ketones
Organometallic Compounds
Palladium