Sequencing of a new HLA-C allele, HLA-Cw*0742, with a novel HLA polymorphism at exon 3

Tissue Antigens. 2006 Dec;68(6):530-1. doi: 10.1111/j.1399-0039.2006.00724.x.

Abstract

The new human leukocyte antigen (HLA)-C allele Cw*0742 was identified by sequence-based typing in a Caucasian bone marrow donor. HLA-Cw*0742 differs from Cw*070201 by a single nucleotide position at codon 113 (TAT --> TTT), giving rise to an amino acid substitution from Tyr to Phe.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alleles*
  • Amino Acid Sequence
  • Base Sequence
  • Exons
  • HLA-C Antigens / genetics*
  • Humans
  • Molecular Sequence Data
  • Polymorphism, Genetic*
  • Sequence Analysis, DNA

Substances

  • HLA-C Antigens
  • HLA-C*07:42 antigen