Abstract
New enantiopure aniline-containing amino alcohols are directly derived from trans-(R,R)-2-(2-nitrophenyl)-3-phenyloxirane, by alternative regioselective double reductions. Subsequent selective alkylation procedures and derivatizations provide a rapid and high-yielding access to different chiral ligands, bases, and benzoxazines, without loss of optical purity.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Amino Alcohols / chemical synthesis*
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Amino Alcohols / chemistry
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Aniline Compounds / chemistry*
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Benzoxazines / chemical synthesis*
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Benzoxazines / chemistry
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Epoxy Compounds / chemistry*
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Ligands
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Molecular Conformation
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Stereoisomerism
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Stilbenes / chemistry*
Substances
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2-(2-nitrophenyl)-3-phenyloxirane
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Amino Alcohols
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Aniline Compounds
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Benzoxazines
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Epoxy Compounds
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Ligands
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Stilbenes
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aniline