Immune recovery following antineoplastic chemotherapy and highly active antiretroviral therapy (HAART) in a child with HIV-1 infection previously unresponsive to HAART

Int J Immunopathol Pharmacol. 2006 Oct-Dec;19(4):919-22. doi: 10.1177/039463200601900422.

Abstract

We report the case of a perinatally HIV-1-infected child, previously immunologically unresponsive to antiretroviral treatments (including the highly active antiretroviral therapy), who instead developed a vigorous and long-lasting immune response after the highly active antiretroviral therapy was associated with antineoplastic chemotherapy undertaken for a B-cell non-Hodgkin bone lymphoma.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Antigens, CD / immunology
  • Antineoplastic Agents / therapeutic use*
  • Antiretroviral Therapy, Highly Active*
  • CD4 Lymphocyte Count
  • HIV Infections / complications
  • HIV Infections / drug therapy*
  • HIV Infections / immunology
  • HIV-1
  • Humans
  • Immunophenotyping
  • Lymphoma, AIDS-Related / complications
  • Lymphoma, AIDS-Related / drug therapy*
  • Lymphoma, AIDS-Related / immunology
  • Lymphoma, B-Cell / complications
  • Lymphoma, B-Cell / drug therapy*
  • Lymphoma, B-Cell / immunology
  • Male
  • Viral Load

Substances

  • Antigens, CD
  • Antineoplastic Agents