Abstract
[Structure: see text] Four subunits of the potent antitumor agent phorboxazole A were constructed; fragments C20-C32 and C9-C19 containing tetrahydropyrans A and B, respectively, were assembled using palladium-catalyzed intramolecular alkoxycarbonylation.
Publication types
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Research Support, N.I.H., Extramural
MeSH terms
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Antineoplastic Agents / chemical synthesis*
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Heterocyclic Compounds, 4 or More Rings / chemical synthesis*
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Oxazoles / chemical synthesis*
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Palladium / chemistry
Substances
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Antineoplastic Agents
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Heterocyclic Compounds, 4 or More Rings
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Oxazoles
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phorboxazole A
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Palladium