Subtype analysis of Cryptosporidium isolates from children in Uganda

J Parasitol. 2006 Oct;92(5):1097-100. doi: 10.1645/GE-843R.1.

Abstract

Cryptosporidium hominis and Cryptosporidium parvum isolates from children in Uganda were characterized by DNA sequence analysis of the GP60 gene. Eight alleles were identified, 4 C. hominis and 4 C. parvum, of which 3 represent new C. parvum families. The data show that it is highly likely that the route of transmission is anthroponotic.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Alleles
  • Amino Acid Sequence
  • Animals
  • Base Sequence
  • Child
  • Child, Preschool
  • Cryptosporidiosis / epidemiology
  • Cryptosporidiosis / parasitology*
  • Cryptosporidium / classification*
  • Cryptosporidium / genetics
  • Cryptosporidium parvum / classification
  • Cryptosporidium parvum / genetics
  • DNA, Protozoan / chemistry
  • DNA, Protozoan / isolation & purification
  • Diarrhea / epidemiology
  • Diarrhea / parasitology
  • Feces / parasitology
  • Female
  • Humans
  • Infant
  • Male
  • Molecular Sequence Data
  • Polymerase Chain Reaction
  • Polymorphism, Restriction Fragment Length
  • Protozoan Proteins / chemistry
  • Protozoan Proteins / genetics
  • Sequence Alignment
  • Sialoglycoproteins / chemistry
  • Sialoglycoproteins / genetics
  • Uganda / epidemiology

Substances

  • DNA, Protozoan
  • Protozoan Proteins
  • Sialoglycoproteins
  • sialoglycoprotein gp60

Associated data

  • GENBANK/AY873780
  • GENBANK/AY873781
  • GENBANK/AY873782
  • GENBANK/AY873783
  • GENBANK/AY873784