Study on the complexation between DNA and cationic porphyrin derivatives

Takako Ohyama; Hajime Mita; Yasuhiko Yamamoto

doi:10.1093/nass/48.1.137

Study on the complexation between DNA and cationic porphyrin derivatives

Nucleic Acids Symp Ser (Oxf). 2004:(48):137-8. doi: 10.1093/nass/48.1.137.

Authors

Takako Ohyama¹, Hajime Mita, Yasuhiko Yamamoto

Affiliation

¹ Department of Chemistry, University of Tsukuba, Tsukuba 305-8571, Japan.

PMID: 17150516
DOI: 10.1093/nass/48.1.137

Abstract

A water-soluble cationic porphyrin, 5,10,15,20-Tetra(N-methylpyridinium-4-yl)-21H,23H-porphyrin has been shown to intercalate selectively into the A3-G4 gap of C-quadruplexed DNA d(TTAGGG)4.

MeSH terms

Base Sequence
Circular Dichroism
DNA / chemistry*
DNA / genetics
Magnetic Resonance Spectroscopy
Porphyrins / analysis
Porphyrins / chemistry*

Substances

Porphyrins
tetra(4-N-methylpyridyl)porphine
DNA