Taking care of Dad's DNA

Genome Biol. 2006;7(12):244. doi: 10.1186/gb-2006-7-12-244.

Abstract

Inheritance of paternal genetic information requires proper sperm development and DNA packaging. A proteomic analysis of sperm chromatin in Caenorhabditis elegans has identified conserved proteins that are important for the transmission of sperm DNA and for male fertility.

Publication types

  • Review

MeSH terms

  • Animals
  • Caenorhabditis elegans / genetics*
  • Caenorhabditis elegans / physiology
  • Chromatin / metabolism
  • DNA / genetics*
  • Fertility
  • Genomic Imprinting*
  • Male
  • Proteome
  • RNA Interference
  • Spermatozoa / metabolism*

Substances

  • Chromatin
  • Proteome
  • DNA