Abstract
A novel quinone derivative, Griseusin C (1), along with a known quinone, Naphthoquinone C (2), was isolated from the lyophilized culture broth of the marine-derived fungus Penicillium sp. The structures were elucidated on the basis of extensive 1 D- and 2D-NMR, as well as HRESI-MS, spectroscopic analysis. The relative stereochemistries of the compounds were assessed by NOESY analysis.
Publication types
-
Research Support, Non-U.S. Gov't
MeSH terms
-
3-alpha-Hydroxysteroid Dehydrogenase (B-Specific) / antagonists & inhibitors
-
Enzyme Inhibitors / pharmacology
-
Horseradish Peroxidase / antagonists & inhibitors
-
Magnetic Resonance Spectroscopy
-
Molecular Conformation
-
Naphthoquinones / chemistry
-
Naphthoquinones / isolation & purification
-
Naphthoquinones / pharmacology
-
Penicillium / chemistry*
-
Spectrometry, Mass, Electrospray Ionization
-
Xanthine Oxidase / antagonists & inhibitors
Substances
-
Enzyme Inhibitors
-
Naphthoquinones
-
griseusin
-
3-alpha-Hydroxysteroid Dehydrogenase (B-Specific)
-
Horseradish Peroxidase
-
Xanthine Oxidase