Deciphering the RNA polymerase II structure: a personal perspective

Nat Struct Mol Biol. 2006 Dec;13(12):1042-4. doi: 10.1038/nsmb1206-1042.

Abstract

This year's Nobel laureate in chemistry is Roger Kornberg. Patrick Cramer gives a personal account of how the Kornberg laboratory determined the structure of the RNA polymerase II core enzyme.

MeSH terms

  • Models, Molecular
  • Nobel Prize
  • Protein Conformation
  • RNA Polymerase II / chemistry*
  • RNA Polymerase II / metabolism
  • Transcription, Genetic / genetics

Substances

  • RNA Polymerase II