AutoGRAPH: an interactive web server for automating and visualizing comparative genome maps

Bioinformatics. 2007 Feb 15;23(4):498-9. doi: 10.1093/bioinformatics/btl618. Epub 2006 Dec 4.

Abstract

AutoGRAPH is an interactive web server for automatic multi-species comparative genomics analyses based on personal datasets or pre-inserted public datasets. This program automatically identifies conserved segments (CS) and breakpoint regions, assesses the conservation of marker/gene order between organisms, constructs synteny maps for two to three species and generates high-quality, interactive displays facilitating the identification of chromosomal rearrangements. AutoGRAPH can also be used for the integration and comparison of several types of genomic resources (meiotic maps, radiation hybrid maps and genome sequences) for a single species, making AutoGRAPH a versatile tool for comparative genomics analysis.

Availability: http://genoweb.univ-rennes1.fr/tom_dog/AutoGRAPH/.

Supplementary information: A description of the algorithm and additional information are available at http://genoweb.univ-rennes1.fr/tom_dog/AutoGRAPH/Tutorial.php.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Algorithms
  • Base Sequence
  • Chromosome Mapping / methods*
  • Computer Graphics
  • Database Management Systems
  • Databases, Genetic*
  • Information Storage and Retrieval / methods*
  • Internet*
  • Molecular Sequence Data
  • Sequence Alignment / methods*
  • Sequence Analysis, DNA / methods*
  • Software
  • User-Computer Interface*