Enhanced catalase-like activity of manganese salen complexes in water: effect of a three-dimensionally fixed auxiliary

Chem Commun (Camb). 2006 Dec 21:(47):4958-60. doi: 10.1039/b608846e. Epub 2006 Oct 9.

Abstract

A new Mn(Salen) complex bearing an ureido group as an auxiliary that is three-dimensionally fixed by a cyclopentane ring fused to the Salen structure was developed. This compound exhibited considerably higher catalase-like activity than the original Mn(Salen), i.e., the cyclopentane-fused Mn(Salen) without the auxiliary, under near-physiological conditions.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Catalysis
  • Crystallography, X-Ray
  • Cyclopentanes / chemistry
  • Enzyme Activation
  • Ethylenediamines / chemical synthesis
  • Ethylenediamines / chemistry*
  • Hydrogen Bonding
  • Hydrogen Peroxide / chemistry
  • Ligands
  • Models, Molecular
  • Molecular Structure
  • Organometallic Compounds / chemical synthesis
  • Organometallic Compounds / chemistry*
  • Stereoisomerism
  • Time Factors
  • Urea / chemistry
  • Water / chemistry

Substances

  • Cyclopentanes
  • Ethylenediamines
  • Ligands
  • Organometallic Compounds
  • Water
  • N,N'-bis(salicylideneamino)ethane-manganese(II)
  • Urea
  • Hydrogen Peroxide