Binding activity of norovirus and sapovirus to histo-blood group antigens

H Shirato-Horikoshi; S Ogawa; T Wakita; N Takeda; G S Hansman

doi:10.1007/s00705-006-0883-z

Binding activity of norovirus and sapovirus to histo-blood group antigens

Arch Virol. 2007;152(3):457-61. doi: 10.1007/s00705-006-0883-z. Epub 2006 Nov 27.

Authors

H Shirato-Horikoshi¹, S Ogawa, T Wakita, N Takeda, G S Hansman

Affiliation

¹ Department of Virology II, National Institute of Infectious Diseases, Tokyo, Japan.

PMID: 17131063
DOI: 10.1007/s00705-006-0883-z

Abstract

Noroviruses (NoVs) and sapoviruses (SaVs) are causative agents of human gastroenteritis. There is increasing evidence that certain human NoV strains bind to histo-blood group antigens (HBGAs). We found that several NoV virus-like particles (VLPs) showed binding activity to HBGAs, while neither SaV genogroup I (GI) VLP nor SaV GV VLP showed such activity.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Blood Group Antigens*
Carbohydrates / physiology
Gastroenteritis / virology
Humans
Lewis Blood Group Antigens / physiology
Norovirus / classification
Norovirus / isolation & purification
Norovirus / physiology*
Saliva / virology
Sapovirus / classification
Sapovirus / isolation & purification
Sapovirus / physiology*

Substances

Blood Group Antigens
Carbohydrates
Lewis Blood Group Antigens