Hypercholesterolemia in Asperger syndrome: independence from lifestyle, obsessive-compulsive behavior, and social anxiety

Psychiatry Res. 2007 Jan 15;149(1-3):321-4. doi: 10.1016/j.psychres.2006.02.003. Epub 2006 Nov 22.

Abstract

We report on elevated total cholesterol and low-density lipoprotein (LDL) levels in 22 individuals with Asperger syndrome compared with well-matched controls, after accounting for lifestyle variables and clinical symptomatology that could affect them. A potential role for dyslipidemia in the pathogenesis of some forms of autism is discussed.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Asperger Syndrome / epidemiology*
  • Asperger Syndrome / physiopathology
  • Body Mass Index
  • Cholesterol / blood
  • Cognition Disorders / diagnosis
  • Cognition Disorders / epidemiology
  • Demography
  • Female
  • Humans
  • Hydrocortisone / urine
  • Hypercholesterolemia / blood
  • Hypercholesterolemia / epidemiology*
  • Life Style*
  • Male
  • Neuropsychological Tests
  • Obsessive-Compulsive Disorder / diagnosis
  • Obsessive-Compulsive Disorder / epidemiology*
  • Obsessive-Compulsive Disorder / psychology
  • Phobic Disorders / diagnosis
  • Phobic Disorders / epidemiology*
  • Phobic Disorders / psychology
  • Severity of Illness Index

Substances

  • Cholesterol
  • Hydrocortisone