Since coronary stent is an important device used in percutaneous support the stenosed artery, its ability to expant the diseased artery wall shall be one of the most significant prerequisites for optimal stent performance. In this paper, the finite element model of coronary stent to resist compressing was set up based on the stent prototype testing. Using the numerical simulation, it was systematically analyzed that the influence of the size of the dilatation of stent and stent strut width and thickness on the stent mechanical properties of the resistance to compressive force applied by two opposite planes. The results show that this resistibility is weakened with the increasing of the final expanded diameter of stent, but increasing the stent strut width or thickness can improve it, and it is equivalent to this improvement to increase the dimension of strut cross section of the stent in the two directions. Experiment result is well consistent with simulation which indicates that the finite element method can substitute for the stent prototype testing to some extent.