Reactive arthritis: defined etiologies, emerging pathophysiology, and unresolved treatment

Infect Dis Clin North Am. 2006 Dec;20(4):827-47. doi: 10.1016/j.idc.2006.09.004.

Abstract

ReA is unique in that it is one of the few disease states of which there is a known trigger. This insight into disease initiation has led to great advances in the pathophysiology. Despite this detailed knowledge, the proper treatment remains elusive. In the years to come it is possible that the specific treatment will be dictated by the triggering microbe.

Publication types

  • Review

MeSH terms

  • Adult
  • Animals
  • Anti-Bacterial Agents / therapeutic use*
  • Antirheumatic Agents / therapeutic use*
  • Arthritis, Reactive* / drug therapy
  • Arthritis, Reactive* / etiology
  • Arthritis, Reactive* / immunology
  • Arthritis, Reactive* / physiopathology
  • Bacterial Infections / complications*
  • Bacterial Infections / microbiology
  • Child
  • Child, Preschool
  • Female
  • Humans
  • Male
  • Mice
  • Prohibitins

Substances

  • Anti-Bacterial Agents
  • Antirheumatic Agents
  • PHB2 protein, human
  • Prohibitins