[The digital criterion of the potential information characteristics of the traditional Chinese medicine chromatographic fingerprints]

Yao Xue Xue Bao. 2006 Sep;41(9):857-62.
[Article in Chinese]

Abstract

Aim: To exploit the characteristic digital criterion for the potential information characteristics of traditional Chinese medicine chromatographic fingerprints, the 37 parameters such as F and I were firstly proposed to disclose the potential information characteristics of traditional Chinese medicine fingerprints.

Methods: The HPLC fingerprints of the Ginkgo biloba extract (GBE) , Ginkgo leaf extract and diphyridamole injection (GLEDI), Ixeris sonchifolia Hance (ISH) and Ixeris sonchifolia Hance injection (ISHI) were compared each other.

Results: As far as the peak signal intensity, the uniform of peak signal, resolution and the fingerprint information were concerned. The GBE fingerprint was better than the GLEDI's, and the ISH fingerprint was also better than the ISHI's, then GBE fingerprint was close to the ISHI' s.

Conclusion: The 37 parameters such as F and I can be used to objectively, authentically and thoroughly display the potential information characteristics of the traditional Chinese medicine chromatographic fingerprints.

Publication types

  • English Abstract
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Asteraceae / chemistry*
  • Chromatography, High Pressure Liquid / methods*
  • Drugs, Chinese Herbal / chemistry*
  • Drugs, Chinese Herbal / isolation & purification
  • Ginkgo biloba / chemistry*
  • Medicine, Chinese Traditional
  • Plant Leaves / chemistry

Substances

  • Drugs, Chinese Herbal