CTX-M beta-lactamase-producing Escherichia coli in French hospitals: prevalence, molecular epidemiology, and risk factors

J Clin Microbiol. 2007 Feb;45(2):620-6. doi: 10.1128/JCM.01917-06. Epub 2006 Nov 15.

Abstract

In 2004, 65 CTX-M-producing Escherichia coli isolates were collected from infected patients in four French hospitals. The blaCTX-M-15 genes were predominant. Pulsed-field gel electrophoresis highlighted a clonal propagation of CTX-M-15-producing strains belonging to phylogenetic group B2, notably in the community. The main risk factors for acquiring these isolates were urinary tract infections or the presence of a urinary catheter in diabetic or renal failure patients.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Electrophoresis, Gel, Pulsed-Field
  • Escherichia coli / classification
  • Escherichia coli / drug effects
  • Escherichia coli / enzymology
  • Escherichia coli / genetics*
  • Escherichia coli Infections / epidemiology*
  • Escherichia coli Infections / microbiology
  • Female
  • France / epidemiology
  • Hospitals*
  • Humans
  • Male
  • Molecular Epidemiology*
  • Phylogeny
  • Prevalence
  • Risk Factors
  • Urinary Tract Infections / epidemiology
  • Urinary Tract Infections / microbiology
  • beta-Lactamases / biosynthesis*
  • beta-Lactamases / genetics

Substances

  • beta-lactamase CTX-M-15
  • beta-Lactamases